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榮獲第十九屆國家新創獎-學研新創獎 得獎名單

創新醫材與診斷技術類
DeepBT腦瘤智慧精準醫療系統：沿時間軸病灶偵測奥放射手術療效預澌
吳育德特聘教授團隊/國立陽明交通大學
技術簡介：
DeepBT針對聽神經瘤、腦膜瘤、腦轉移瘤三種主要腦瘤磁振影像，使用獨特雙通道U-net深度捲積神經網路進行三維自動腦瘤圈選，克服影像軸向與平面解析度不同、不同類型腫瘤數量不均，體積大小位置不一、術前術後腫瘤變化與對位等問題，計算多時間點腫瘤體積變化，並以影像組學於術前預測療效，協助醫師診療決策。


智慧醫療與健康科技類
影像引導 Veress 針於腹腔鏡手術之氣腹建立
郭文娟特聘教授團隊/國立陽明交通大學
技術簡介：
郭文娟所長團隊研發創新技術可即時識別氣腹針針尖位置，將腹膜通路的盲插技術轉化為可視化程序，大大提高氣腹建立的有效及安全性，是目前唯一能達到眼見為憑的影導式穿刺針技術。報導連結

 

打造健康福祉科技人力第一品牌-陽明交大醫工系孵育下世代創新醫材領航者

陽明交大生物醫學工程學系是全臺國立大學中首個具有大學部、碩士班與博士班的生物醫學工程學系，至今已有近40年歷史，擁有兼具工程學核心與基礎醫學的課程，讓學生進入臨床實地尋找醫療痛點， ​​並攜手產業共同研發醫材，持續讓學生如沃土中的種子般發芽茁壯，成為國內相關科系的標竿。

橋接工程與生物醫學 打破醫師與工程師間的高牆
生醫電子、生物力學、生醫材料  三大領域教師 引領人才豐厚產業
教學合作醫院  深化臨床需求與創新研發
報導連結：環球生技 https://news.gbimonthly.com/tw/article/show.php?num=55133

 

國科會補助產學計畫成果-新式客製化面中部金屬3D列印骨板登記上市
臨床上，可能因為車禍外傷、外力撞擊或是腫瘤性疾病造成面中部骨折缺陷，若沒有受到合適的治療，將可能導致顏面部外觀不對稱、咬合不正和眼睛產生複視等問題，目前臨床上最有效的治療是由整形外科醫師利用傳統微型骨板進行面中部骨折復位與重建手術，然而卻還面臨定位不佳及復位不穩定等問題。報導連結：經濟日報



國立陽明交通大學生物醫學工程學系林峻立特聘教授主持國科會工程處產學合作研究計畫，精進開發出一項具導引定位/固定/力學穩定性的客製化(patient-specific)面中部金屬3D列印骨板，其單片式骨板開發不但根據國人影像資料庫而設計，同時可依據病患的顏面曲率製作沖壓模具而將骨板成型，此創新的設計及成型法，可有效輔助游移骨復位，亦可承受面中部支撐力學。此項開發已通過法規所要求之生物相容性及功能性測試，且通過衛福部食藥署(TFDA)認證登記上市(衛部醫器製字第006336號)，目前已於各大醫院臨床測試中。
計畫團隊在客製化面中部骨板生物力學分析中，證實目前手術使用的市售微型骨板的骨頭會產生應力集中，因此無法傳遞咬合力量，會導致骨應力傳遞不佳復位失敗。而透過資料庫設計的面中部骨板功能性測試則可符合上市之法規標準，其彎曲強度均優於市售微型骨板。
林峻立教授現任國立陽明交通大學生物醫學暨工程學院院長，亦擔任創新醫材轉譯研發中心主任。他於2021年以「手持式高齡智能舌壓量測與復健系統」榮獲第17屆國家新創獎。林峻立教授所帶領的「生醫工程分析實驗室」擁有電腦輔助工程設計及製造(CAD、CAM)、電腦輔助工程分析及有限元素分析(CAE、FEA)、影像處理重建、3D列印/積層製造、拓樸最佳化、晶格微結構設計、靜/動態功能性測試、客製化生物力學實驗及音洩破壞等核心技術，主要應用於臨床的骨科、牙科、復健科、骨腫瘤科、脊椎骨科、整形外科、神經外科、及齒顎矯正科，聚焦於醫療植入物從臨床需求、產品設計、小量試產、臨床前測試及輸出報告的整個開發流程，後續再輔導廠商將這些有效報告提交給TFDA/FDA進行產品查驗登記，通過之後產品即能上市應用於臨床。
林峻立教授表示，成功的醫材開發必須和臨床醫師密切合作，從臨床需求出發，然後將學校的技術應用於醫材的設計、試量產和測試，在通過認證與上市之後，還要能在臨床的應用落地。同時，因為醫療器材牽涉到各國的相關法規，因此醫學工程教育及醫材產業需熟習各國法規及其修訂，與時俱進。
臺灣的醫材產業已經過政府長期的扶植和推動，林峻立教授指出，現階段的當務之急是要擴大市場，以優良的產品創造出更大的經濟效益。在臺灣，可以透過各種方式鼓勵國人使用國產醫材，從而累積臨床數據，持續精進產品，並進行臨床試驗發表。他說：「透過臨床使用數據的公開發表，才會讓全世界看到臺灣研發的新創醫療器材，即使與國外的產品相比也絲毫不遜色，甚至更好，全世界就會看到我們的存在點。當臨床使用數據變得龐大，才能在國際上大量曝光，要讓全世界的人都知道，才有辦法跟全世界競爭。」
林峻立教授觀察到東南亞的國家對於通過TFDA認證的醫材接受度相當高，因此，建議政府部門結合醫師和醫材產業，深耕南向市場。他說：「把產品帶出去，廠商有一定的經濟效益跟收入，臺灣的醫材產業才能有正向的循環。廠商賺錢，我們在學校投注心血培育的優質醫工人才，才能灌注到臺灣的醫材產業，締造經濟效益。」

2022.12.02 本院師生70人參訪

展覽名稱:「台灣醫療科技展」暨「AI智慧醫療器材與永續創新技術趨勢研討會」

展覽地點: 台北南港展覽 1館

協辦單位:教育部精準健康跨領域人才培育計畫

 

現場展區特色
 (1) 特色醫療 (2) 智慧醫院、醫材設備與供應鏈 (3) 精準檢測、生技新藥與細胞治療 (4) 新創技術Inno Zone專區
(5) 智慧健康科技與預防醫學(6) 運動健康科技 (7) 無齡健康生活 (8) 農業生技與食安健康
 





 

Technology Name: DeepBT Brain Tumor Smart Precision Medical System: Along-Time Axis Lesion Detection and Radiosurgery Efficacy Prediction
Project Team: Dr. Wu Yu-Te and Dr. Lu Jia-Feng


Technical title: Near-infrared dual-mode fluorescence + photoacoustic 3D small animal imaging system combined with homemade polymer fluorescence/photoacoustic dye for whole-body and tumor vascular imaging in mice
Project Team: Dr. Jiang Huihua and Dr. Li Yizhan



Exhibit Name: Simulating Precise Hearing Organs: Deep Learning Class Neurointelligence Network Noise Cancellation Method for Next Generation Electronic Ear
Project Team: Dr. Yinghui Lai

Yang Ming Jiaotong University is the first to obtain a medical device manufacturer and vendor license


"With the support of President Chih-Hung Lin, the Center for Innovative Medical Material Translation and Research (CIMR) has compiled and applied for two licenses for medical device vendors and manufacturers (medical software and implants) in August and September of this year respectively, which will give new impetus to the commercialization of medical devices.

According to the new system of the Medical Device Control Act, research institutions can apply for design-based medical device manufacturing and sales licenses with the consent of the competent authorities. This measure will greatly help to improve the quality, value, and technology of medical devices developed by research institutions, as well as to maximize the economic benefits of the National Science Council's grant program. Therefore, the University actively applied for the new system as soon as it was launched, and was successfully granted the two permits.

Professor Lin Junli, Director of the Center for Innovative Medical Material Translation and Research, said that the successful development of medical devices is not simply the application of engineering technology to biomedicine, but must meet the premise of "clinical needs", integration of regulatory testing / preclinical testing (or clinical testing), the establishment of industrial QMS and other stages of work, before further testing and registration for certification, and then can enter the "clinical implementation" The next step is to enter into "clinical implementation" and other applications. Therefore, the role of the Center for Innovative Medical Material Translation and Research (CIMR) in our university is to "promote the linkage of biomedical engineering," "integrate health and medical resources," "develop medical material industry clusters," and "promote innovative research and development axes" as the main axes, and to fully develop Med-Tech as the goal, injecting huge research and development translation energy for the development of medical devices in Taiwan.


The "Center for Innovative Medical Material Translation and Research" team is composed of five main research and development areas: precision medical implants, high-value biomedical materials, precision diagnostics and smart assistive devices, precision medical imaging and biomedical sensing care.
The acquisition of medical device vendor and manufacturer licenses not only helps the university's R&D team shorten the time to market for medical materials, but also strengthens the development of smart medical materials after the university's merger. Take medical software development as an example, after the pre-clinical testing and validation of the software, the QMS system can be certified; after passing the TFDA inspection by the Ministry of Health and Welfare, the manufacturing and inspection can be registered.

By obtaining the medical device manufacturer's license and sales license (certification numbers MD6101000739 and MD6201041374), the university will soon apply for medical device quality management system (QMS) certification by the Center for Innovative Medical Material Translation and Research and the university's medical software R&D team. The Center will apply for medical software registration with the TFDA of the Ministry of Health and Welfare.

In addition, the Center for Innovative Medical Material Translation and Research has obtained a medical device manufacturing and sales license, and has applied with the College of Biomedical Sciences and Engineering for the Ministry of Labor's Quality Management System Training Institute for Human Resource Development certification. In the future, our school will be able to undertake the certification course for medical material technician training of TFDA, in order to enhance the professional skills of practitioners and contribute to the development of medical material industry in Taiwan.



Medical device vendors (from left to right), manufacturer's licenses, and the Ministry of Labor's Human Resources Development and Quality Management System Training Institute Certification

(Chinese Health Network Reporter Man-Ying Huang / Taipei © Provided by Chinese Health Network)

It's amazing! The palm-sized Nephila pilipes spider is intimidating, but the spider's silk can be used to measure blood sugar and serve as a diabetes management tool. Prof. Cheng-Yang Liu and Ms. Xuan-Bei E of the Department of Biomedical Engineering, Yang Ming Jiaotong University, have successfully developed a fiber optic glucose sensor using the spider's spider silk.

Amazing! A spider with a human face spits out spider silk, but it can detect blood sugar! A new breakthrough in measuring blood glucose with fiber optics © by Chinese Health Network

With the aging population, diabetes is now a common disease. Patients who monitor their blood glucose by puncture at home are not only prone to the risk of infection, but also the puncture needle becomes medical waste after one use, so scientists are always striving to develop more convenient and real-time blood glucose detection methods.

Unlike traditional optical fibers made of glass or plastic, spider silk not only has good ductility and physical properties such as light wave transmission, but also has a high degree of biocompatibility, making it very suitable for use in the human body. After obtaining natural spider silk from a live spider, Prof. Cheng-Yang Liu's research team, in collaboration with Taipei Medical University and Taiwan Instrument Technology Research Center of National Taiwan Research Institute, first stabilized the spider silk structure with light-curing resin, and then sputtered a thin nanogold shell on the surface of the cured spider silk with an oblique thin-film sputtering technique to increase the sensitivity of the spider silk fiber to sugar concentration. The final product is a fiber optic sensor with a diameter of about a hair and visible to the naked eye.

The process of spider fiber fabrication. (Photo courtesy of Yang Ming Jiaotong University) © Courtesy of Chinese Health Network

Through the optical physics principle of surface plasmon resonance (SPR), scientists can calculate the refractive index of different sugars on metals to know their concentration changes. The optical sensor developed by Prof. Cheng-Yang Liu has been experimentally proven to maintain the same sensitivity over a year and to function normally at room temperature and human body temperature.
The research team led by Prof. Cheng-Yang Liu uses spider fiber to measure blood glucose, which can be a tool for future diabetes management. (Photo courtesy of Yang Ming Jiaotong University) © Courtesy of Chinese Health Network
In fact, in order to find suitable materials, the R&D team tried two to three different species of spiders and also caught spiders on campus for experiments, but unfortunately, the quality of spider silk was not very stable, and only after many attempts did they choose the sphinx spider as the main target. In order to get high quality spider silk, the R&D team must also learn how to keep spiders and design silk extraction methods.

The spiders were not only huge, but they were also afraid of spiders with long faces on their backs at first. In the process of making the spider silk fiber, the research team also tried a variety of resins, gold, silver, copper and other metals, so they met the bosses of reptile stores, resin manufacturers, etc., which is considered an unexpected harvest.

Prof. Cheng-Yang Liu said that diabetic patients need to monitor their blood sugar before and after meals, and a sensor that can be used in the human body for a long time and measure blood sugar accurately in real time will not only solve the patients' problems, but also achieve the goal of precision medicine and benefit more chronic disease patients.

In addition to Yang Ming Jiaotong University, the research results also include the participation of researcher Weijun Chen, researcher Zheqin Chen, and professor Jiaxiong Cheng from the Department of Medicine, National Taiwan Research Institute. The research results will be published in the September issue of Biomedical Optics Express and selected as an Editor's Choice for the publication.

Raman spectroscopy uses the scattered wavelength of light incident on an object to measure the material (the material in the picture is molybdenum disulfide)
The natural residual concentration of mercury in cosmetics in China is 1 ppm, but the Institute of Biomedical Photonics, Yang Ming Jiaotong University has successfully used magneto-plasmonic nanoparticles in combination with laser light, and surface-enhanced Raman scattering (SERS) to reach the measurement limit of 2 ppb. SERS) to reach the measurement limit of 2 parts per billion (0.2 ppb). This technique has the potential to bring a more convenient approach to heavy metal detection.

The Food and Drug Administration prohibits the addition of heavy metal mercury to cosmetic products except for natural residues, but because mercury inhibits the activity of tyrosinase in the skin and reduces melanin production, there are still unscrupulous operators who add mercury to them. Therefore, the heavy metal content of cosmetic whitening products has been the focus of inspection. However, most of these heavy metal tests can only be done in laboratories using huge instruments such as mass spectrometers.

The principle of Raman Spectroscopy, where the wavelength of light scattered into an object differs from the original wavelength, depending on the material of the object, has been considered to have potential for material analysis. However, the scattered signal is small and often disturbed by the light emitted from the object itself after illumination, making the signal difficult to resolve.



Prof. Xue Te, Institute of Biomedical Photonics, Yang Ming Jiaotong University
To overcome this problem and make the theory applicable in practice, a common method is to cover the sample with a metallic substrate, i.e., a Surface-Enhanced Raman Scattering Substrate. Prof. Surojit Chattopadhyay, M.S., M.S., and Dr. Akash Gupta of Institute of Biomedical Photonics, Yang Ming Jiaotong University (YJTU), fabricated iron oxide nanoparticles and coated them with a layer of metallic silver, and used a magnet to make the iron oxide nanoparticles aggregate.

This technique of using laser light to combine nanoparticles to enhance Raman spectroscopy through surface enhancement has been used to measure the natural residue of mercury in commercially available whitening cosmetics, and it can detect the limit of mercury ion concentration up to 2 ppb (0.2 ppb), which is much lower than the current requirement of 1 ppm in Taiwan. This shows that this technology is not only more sensitive in detection but also has the potential to be applied to detection.



500 nanometers of magnetic plasma nanoparticles
Professor Sitt said that if cosmetics contain heavy metals, they may be poisoned by long-term trace absorption through the skin. Although today's heavy metal detection methods are accurate, they require a large number of samples and professional technicians to operate in the laboratory. The process of using Raman spectroscopy to detect substances is simple and fast, as long as the light can be irradiated substances can be detected, including solids, liquids, gases, etc..

Many scientists have invested in the development of nanosubstrates for surface-enhanced Raman scattering in the hope that this theory can be put into industrial applications. This time, Yang Ming Jiaotong University has successfully found a nanoparticle that can amplify Raman signals and be used for detecting cosmetics by wrapping iron oxide with a silver coating; how to steadily regulate the structure of metal nanoparticles and create a reusable substrate is a challenge for future commercialization. This study was published in 2021 in Sensors and Actuators B: Chemical, No. 337, an important journal for photoelectric sensing technology.


Source: Laser light + metal nanoparticles push the limit of mercury detection to 0.2 ppb at Yang Ming Jiaotong University - NYCU National Yang Ming Jiaotong University

The Department of Biomedical Engineering at Yang Ming Jiaotong University, Professor Zhong Jiwen said that silk protein has a proven track record as a biomaterial because of its high biocompatibility, and he has also used the same material to make heart muscle patches that repair heart muscle cells.
In Taiwan, more than 40,000 people are equipped with pacemakers, and now scientists have discovered a biomaterial made from silk that can convert heart muscle cells that would otherwise not discharge electricity into heart rhythm cells that can beat themselves, allowing the heart to resume beating. This major discovery has changed the way people think about the treatment of arrhythmias and has led to a study from Taiwan that was featured in the top international journal Nature Biomedical Engineering.

The heartbeat of about 60-100 beats per minute comes from the discharge of the sinoatrial node of the pacemaker, a spontaneous electric current that allows the heart's muscles to contract and pump blood throughout the body. However, as we age, the organ always wears out over time. Because of the aging failure of the pacemaker rhythm cells, a slow heartbeat may occur, such as sinus syndrome and atrioventricular conduction block, resulting in weakness, difficulty breathing, fainting, and even sudden death, with a prevalence of about 1% to 2%. The prevalence rate is about 1% to 2%. This figure may be higher in elderly people over 65 years old.

The current treatment for this heart-borne disease is a two-hour surgery to install a pacemaker in the body. However, the pacemaker requires battery replacement in about 6 to 8 years, invasive surgery also has the risk of surgical infection, and even in the era of the prevalence of cell phones, such installation of electronic pacemaker patients must also be as far away from the heart as possible, so scientists invariably hope to find alternative methods.

The research team, led by Professor Zhong Jiwen of the Department of Biomedical Engineering at Yang Ming Jiaotong University and Dr. Yu-Feng Hu of the Department of Cardiology at the Taipei General Hospital, successfully used silk from a modified farm in Miaoli, Taiwan, to purify silk protein gel, which was injected into the hearts of mice to convert heart muscle cells that would otherwise not beat into pacemaker rhythm cells that could discharge electricity. This is the first time that silk proteins have been used as surgical sutures and artificial dressings, but this is the first time that silk proteins have been found to have mechanical and biochemical properties, as well as cellular transformation and bioelectricity production.

In animal studies, the research team found that silk proteins can be used as biomaterials to initiate the ectopic expression of calcium mucin in cardiac muscle cells, initiating a series of downstream mechanisms that allow the heart to be recharged and restored. In other words, the research team has re-generated the cells that discharge electricity from the heart. In this way, once the sinus node ages or becomes diseased, the newly generated cells can take over the important role of discharging electricity to keep the heart beating.



Dr. Yu-Feng Hu and Prof. Ji-Wen Chung of the Department of Cardiology at Northwestern University have discovered that biomaterials made from silk proteins can convert cardiac muscle cells that would otherwise not discharge electricity into self-beating heart rhythm cells, allowing the heart to resume beating.
The company's main goal is to provide the best possible service to its customers.

The research team tried dozens of biomaterials and finally found a way to use silk protein, said Professor Zhong Jiwen of the Department of Biomedical Engineering at Yang Ming Jiaotong University. He said that silk protein is highly biocompatible as a biomaterial, in fact, there are signs, including artificial skin, surgical sutures, wound dressings can be found in its trace. He has also used the same material to make myocardial patches to repair heart muscle cells, showing that domestic silk has the potential for advanced medical applications.

Dr. Yu-Feng Hu and Professor Chung met at a conference four years ago, sparking this collaboration. Dr. Yu-Feng Hu describes how he found that the heart muscle cells "came to life" and kept beating when he incubated them on Chung's silk proteins, and began the research to find out why.

The study was published in Nature Biomedical Engineering, a division of Nature, and proved that in addition to stem cell culture and gene therapy, biomaterials also have the potential to treat heart-borne diseases.

Source: Silkworm protein restores a heart that has stopped beating, and a team at NYCU successfully uses biomaterials to convert heart muscle cells into rhythm cells - NYCU

Deputy Director of Social and Family Affairs Department, Ministry of Health and Welfare, Mei-Mei Chang (left) presents a certificate of appreciation to Director Li Shu-Ching
This year also marks the 20th anniversary of the ICF and Assistive Technology Research Center, a university-level research center of National Yang Ming University of Transportation, helping to promote assistive device services for people with physical and mental disabilities, and the establishment of the Multifunctional Assistive Device Resource Integration and Promotion Center commissioned by the central government. At the National Liaison Meeting on Nov. 26, the Deputy Director of the Social and Family Affairs Department of the Ministry of Health and Welfare, Mei-Mei Chang, presented a certificate of appreciation to the team led by the Director of ICF, Shu-Ching Li, for their contribution to the development of assistive technology services in China over the past 20 years.

In her acceptance speech, Ms. Lee talked about the 20 years of her life spent in running the Center and building the national assistive device service system, and cited the following five major achievements of the Center in the past 20 years.

First of all, the center introduced the core concept of the international assistive devices classification standard - ISO 9999 at the early stage of the development of the assistive devices service system in China. It is the first achievement of the Center to shape the development of assistive services in China from a broad perspective.

Furthermore, since 2005, the team of the Center has been commissioned to build the "Aids Resource Portal" in Taiwan, which integrates all the information on aids in the fields of industry, government, academia, research, and medicine, and is a valuable and leading platform of aids information in the world. This is the second major achievement of the Center.



The Social Welfare Administration of the Ministry of Health and Welfare thanks the ICF and Assistive Technology Research Center of Yang Ming Jiaotong University for its 20 years of assistance in promoting the development of assistive technology services.
In addition, with the joint efforts of all of us, the new system of ICF for the protection of the rights of the physically and mentally disabled was launched in 2012, making "assistive devices services" a statutory service for the physically and mentally disabled in China. As a WHO observer in 2019, Director Li was pleased that our country has a state-of-the-art system of assistive devices that is proud of the world. Helping to plan and promote a new system of assistive services based on professional understanding and meeting needs is the third major achievement of the Center.

The key to the success of the auxiliary service is not only the training of human resources and the professional quality management of the auxiliary service centers, but also the experience of our country over the years shows that strengthening the support function of county and municipal governments through evaluation indicators and guiding the integration of services between county and municipal governments and auxiliary service centers, instead of focusing only on the auxiliary service centers, is a pragmatic and highly effective approach, which is also a model worthy of international promotion. The fourth major achievement of the Center is to establish evaluation indicators that effectively promote the success of the auxiliary aid services in Taiwan.

Lastly, the ICF and Assistive Technology Research Center of National Yang Ming University of Transportation has been hosting the Assistive Devices and Long-term Care Exhibition since 2016, which is an international professional exhibition with more than 100,000 visitors for three consecutive years. Among the many functions of this exhibition, it provides a positive learning platform for assistive technology professionals to learn about the latest international assistive technology development, and through a more comprehensive understanding of the products and manufacturers, it will be conducive to the improvement of professional services. The fifth major achievement of the center is to successfully link the three elements of assistive technology development: professionals, industry and products.



2021 Aids and Long-term Care Exhibition
Director Lee said that there are still many goals to be developed in the future, which need to be improved step by step in a competitive manner.

First of all, 2022 will be a new era for our country's auxiliary aids services, including the draft amendment of the benchmark table of auxiliary aids for the physically and mentally disabled, which has been notified through the efforts of the Social Welfare Department and is scheduled to be officially implemented on September 1 next year. It is expected that the new system of auxiliary aids will be implemented smoothly next year, including the continued support of county and municipal governments and the smooth transformation of auxiliary aids centers, so as to successfully move to the next stage.

In addition, for the successful implementation of the new system of aids for the mentally and physically disabled and Long Term Care 2.0, the participation of inter-ministerial units is very important, including the effective performance of the functional roles of each ministry and the positive interaction and cooperation between ministries.

Finally, the current situation shows that the volume of long-term care assessment services in most county and city auxiliary care centers has increased significantly, which indicates the inevitable trend of further integration of mental and physical disabilities and long-term care services in the social welfare system, including the integration of auxiliary care center audits by the central authorities.

Under the leadership of Director Li, the Multifunctional Assistive Devices Resource Integration and Promotion Center has assisted the Ministry of Health and Welfare in the vertical and parallel coordination of various units for 20 years, and has worked hard to promote the policy of assistive device services, the training of assistive device professionals, and the development of the industrial market. We look forward to your continued support and to working together for a better and more prosperous future!



Source: 20 Years of Glory! "ICF and Assistive Technology Center of Yang Ming Jiaotong University Receives Certificate of Appreciation for 20 Years of Contribution - NYCU National Yang Ming Transportation University

Congratulations to Professor Wang, Yang, and Liu for winning the top 2% of the world's top scientists!