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陽明交大AI腦瘤偵測獲TFDA批准 國內首款 多腦瘤智慧醫材

今(2)日，陽明交大宣布，其自行研發的AI腦瘤輔助偵測系統和等速肌力試驗評估系統兩項醫材，已正式取得衛福部上市許可。此款AI腦瘤輔助偵測系統，可協助針對聽神經瘤、腦膜瘤與腦轉移瘤等三種主要腦癌的磁振造影(MRI)進行判讀，是國內首見針對多種腦瘤自動偵測與圈註的智慧醫材軟體。研發此AI技術的生醫光電研究所教授吳育德表示，過去，腦腫瘤的檢測仰賴醫師檢視影像並手動圈註，在放射治療前，醫師通常得審視大量的影像資料來評估腫瘤體積、位置、有無水腫等病理特徵。


研究團隊將從臺北榮總與臺中榮總取得超過20萬張的二維影像，給人工智慧學習後，才能克服目前臨床磁振造影影像軸向與平面解析度不同，不同腫瘤類型與大小位置不一等難題，讓人工智慧能正確判讀腦瘤，可大幅縮減臨床治療所需成本。另一項獲得核可的醫材為針對幼童及中風長者的口腔等速肌力試驗評估系統，可以用來解決臨床上對於唇肌力復健的需求，協助患者進行有效的唇肌力訓練。


推動醫療器材商品化的陽明交大創新醫材轉譯研發中心主任林峻立教授表示，大學常是醫材設計研發的火車頭，但過去只有業者才能申請查驗登記，影響商品化的時程。林峻立進一步表示，《醫療器材管理法》鬆綁後，讓大學除了研發外也可以兼為醫材業者，有益促成更多研發成果商品化，朝臨床落地應用的目標邁進。陽明交大表示，創新醫材轉譯研發中心今年4月才以3D列印下顎骨板技術，通過食藥署「醫療器材品質管理系統」(Quality Management System, 簡稱QMS)。陽明交大成為同時擁有醫材品質管理系統，第一級與第二級醫材許可的首間大學。林峻立表示，為了提升大學醫材研發品質，替民間創造價值與技轉機會，陽明交大將先以醫用軟體及輔具醫材為主軸，藉由臨床驗證、法規、品質確認及商業化的一條龍服務，協助加速醫材開發，建構各類型產品的QMS，並取得查驗登記。
報導連結：環球生技

Supported by the Medical Device Innovation and Translational Center and the College of Biomedical Engineering at our university, and under the guidance of Professor 賴穎暉 from the Department of Biomedical Engineering, a research team composed of five students —張育哲, 鍾伃晴, 單婉菱, 張書寧 and 張舒喬—participated in the 16th 2023 Global Student Innovation Challenge - Rehabilitation Engineering and Assistive Technology, held in Thailand.

Amid fierce competition from 33 teams worldwide, the team stood out with their outstanding performance and won the Gold Award in the Technical Category. The award was personally presented by Princess King Kanitthathiraj Chao, a member of the Thai royal family.


The team’s competition project was the Dysarthria Voice Conversion (DVC) System, which integrates three core technologies: patient-like data generation, automatic speech recognition (ASR), and text-to-speech (TTS). Collaborating with APrevent Medical Ltd, the team successfully developed an innovative assistive communication device. This device can instantly convert the speech of individuals with dysarthria, significantly improving the clarity of their speech and enhancing their quality of life, helping them regain confidence in speaking.

Professor Ying-Hui Lai expressed heartfelt gratitude to the university and the Ministry of Education's Cross-Disciplinary Talent Cultivation Program for the Precision Health Industry for their resource support. This support allowed the team to systematically learn about the development of intelligent medical devices and enabled their research results to be applied in practice, fostering innovation in the precision health industry.

The outstanding team has gained valuable cross-disciplinary competition experience, strengthened innovative thinking, and enhanced their international competitiveness by participating in domestic and international contests. Professor Lai also acknowledged the selfless guidance of the industry mentors involved in the program, as well as the dedication and effort of the team members. He hopes that more current students and alumni will take part in this series of enriching training programs.

For more details, please refer to the official website of Thailand: [Insert Website Link or Specific Details].

Our school takes great pride in the Medical Device Innovation and Translation Center as well as the Department of Biomedical Engineering. Under the mentorship of Associate Professor Ying-Hui Lai, a team composed of 張育哲、鍾伃晴、單婉菱、張書寧, and 張舒喬 participated in the '2023 Global Student Innovation Challenge - Rehabilitation Engineering and Assistive Technology' held in Thailand ,bringing great honor to our school .


The project of the team focuses on the topic of "Dysarthria Voice Conversion" collaborated with the company APrevent Medical to successfully develop an innovative communication aid. This device not only assists dysarthric patients in improving their vocal expression but also significantly enhances their efficiency in communication, and further promotes their  speech communication abilities. Students from National Yang Ming Chiao Tung University stood out among the fierce competition from 33 participating teams worldwide, and won the gold medal. The award was presented by Princess King Kanitthathiraj Chao from Thailand's royal family in person.

The core technology of the "Dysarthria Voice Conversion (DVC)" project comprises three main parts: patient-like data generation technology (data augmentation), automatic speech recognition, and text-to-speech conversion. Additionally, our entry takes a step further by proposing the utilization of optical sensing technology to reduce the required vocal effort for patients, thereby achieving a more effortless communication in real-time experience.

Based on the current experimental results, our proposed DVC system demonstrates superior conversion capabilities, leading to a significant improvement in the clarity of patients' speech. This finding clearly indicates that the DVC system we introduced in this competition holds the potential to assist patients with speech disorders in enhancing communication effectiveness, further improving their quality of life.




It is worth mentioning that President 林奇宏 gave unwavering support in the "Ministry of Education's Interdisciplinary Talent Development Program in the Precision Health Industry - Smart Medical Devices Field." This program not only encompasses well-designed educational courses on medical device development but also covers both theoretical and practical aspects. Participating students can systematically and effectively learn comprehensive product development methods, enterprise operational planning, as well as innovative and entrepreneurial logical thinking. Professor Lai expressed deep gratitude for the selfless guidance provided by the course instructors and commended the team members for their dedication and efforts. He looks forward to the participation of more current students and alumni in this enriching training program.

Congratulations to the Outstanding Administrative Staff Award Recipients of 2022!


Department of Biomedical Engineering: Associate Coordinator 陳星宇
Graduate Institute of Biomedical Optomechatronics: Associate Coordinator 何孟芳

榮獲第十九屆國家新創獎-學研新創獎 得獎名單

創新醫材與診斷技術類
DeepBT腦瘤智慧精準醫療系統：沿時間軸病灶偵測奥放射手術療效預澌
吳育德特聘教授團隊/國立陽明交通大學
技術簡介：
DeepBT針對聽神經瘤、腦膜瘤、腦轉移瘤三種主要腦瘤磁振影像，使用獨特雙通道U-net深度捲積神經網路進行三維自動腦瘤圈選，克服影像軸向與平面解析度不同、不同類型腫瘤數量不均，體積大小位置不一、術前術後腫瘤變化與對位等問題，計算多時間點腫瘤體積變化，並以影像組學於術前預測療效，協助醫師診療決策。


智慧醫療與健康科技類
影像引導 Veress 針於腹腔鏡手術之氣腹建立
郭文娟特聘教授團隊/國立陽明交通大學
技術簡介：
郭文娟所長團隊研發創新技術可即時識別氣腹針針尖位置，將腹膜通路的盲插技術轉化為可視化程序，大大提高氣腹建立的有效及安全性，是目前唯一能達到眼見為憑的影導式穿刺針技術。報導連結

Technology Name: DeepBT Brain Tumor Smart Precision Medical System: Along-Time Axis Lesion Detection and Radiosurgery Efficacy Prediction
Project Team: Dr. Wu Yu-Te and Dr. Lu Jia-Feng

Technical title: Near-infrared dual-mode fluorescence + photoacoustic 3D small animal imaging system combined with homemade polymer fluorescence/photoacoustic dye for whole-body and tumor vascular imaging in mice
Project Team: Dr. Jiang Huihua and Dr. Li Yizhan


Exhibit Name: Simulating Precise Hearing Organs: Deep Learning Class Neurointelligence Network Noise Cancellation Method for Next Generation Electronic Ear
Project Team: Dr. Yinghui Lai

Congratulations to Professor Wang, Yang, and Liu for winning the top 2% of the world's top scientists!

Congratulations to Jiang Hui-hua from the Department of Medical Engineering for leading the team to invest in the research and development of innovative medical materials "Ultrasonic Anesthesia Probe" won the Ministry of Science and Technology Seedling Program

The Taipei City Government organized the "2021 Taipei Biotechnology Awards", and the award ceremony was held on the morning of September 11, when Mayor Ko Wen-Che unveiled the winners of the "Innovation Technology Award", "International Advancement Award", "Technology Transfer Cooperation Award" and "Cross-Disciplinary Excellence Award". This year, during the epidemic prevention period of the new crown, the award ceremony was held in accordance with the epidemic prevention regulations and encouraged outstanding biotechnology research institutions and enterprises in Taiwan through a concrete commendation ceremony.

The "Design and Development of Parametric Implants for Dental Implants with Optimized Structure of the Mandibular Region" developed by Professor Lin Junli of the Department of Biomedical Engineering and Dr. Wu Zhengxian of the Department of Oral Surgery of Taipei Veterans General Hospital won the "Excellent Award for Technology Transfer Cooperation". The main theme of the research and development is to integrate CT scan, optimized structural design, computer-aided simulation analysis and metal 3DP printing technologies to develop a customized reconstructed metal implant for patients with extensive jaw bone defects, which has functional features such as segmental occlusion biomechanics, lightweight structural design and can be used with post-operative dental implants. After the company has passed the QMS certification for medical devices, the implant will enter clinical trials for the benefit of patients with extensive mandibular deficiencies, so that patients can have their jaws reconstructed with a combination of cosmetic, biomechanical, and occlusal considerations and improved quality of life.


Professor Lin Junli and Mayor Ko Wen-je

Interview with Professor Lin Junli

2021 Taipei Biotechnology Award Certificate

恭喜林峻立特聘教授榮升本院第六任院長